One significant slave uprising in Black history was the Nat Turner Rebellion, which took place in 1831 in Southampton County, Virginia. Nat Turner, an enslaved preacher, led a group of slaves in a violent revolt against their white enslavers. The rebellion resulted in the deaths of around 60 white people before it was ultimately suppressed by local militia and state authorities.

Another well-known slave uprising is the Haitian Revolution, which began in 1791 and culminated in the establishment of the first independent Black republic in the Western Hemisphere in 1804. Led by figures such as Toussaint Louverture and Jean-Jacques Dessalines, enslaved Africans in the French colony of Saint-Domingue (now Haiti) rose up against their oppressors and successfully overthrew the colonial government, freeing themselves from slavery and colonial rule.

These and other slave uprisings throughout history were pivotal moments in the struggle for freedom and equality for Black people, challenging the institutions of slavery and oppression and inspiring future generations of activists and freedom fighters.