James Meredith was a significant figure in Black history as the first African American to enroll at the University of Mississippi in 1962. His admission was a pivotal moment in the Civil Rights Movement, as it challenged the segregationist policies of the time. Meredith's enrollment at Ole Miss was met with violent opposition, leading to riots and the intervention of federal troops to ensure his safety and right to attend the university. Despite facing numerous obstacles and threats, Meredith persevered and graduated from Ole Miss in 1963.

Meredith's actions at the University of Mississippi helped to advance the cause of civil rights and paved the way for other African Americans to access higher education in formerly segregated institutions. He continued to be an activist throughout his life, advocating for civil rights and education, and his legacy continues to inspire others in the ongoing fight for racial equality.