One significant Black-led labor strike in Black history was the Memphis Sanitation Strike of 1968. The strike was sparked by the deaths of two African American sanitation workers, Echol Cole and Robert Walker, who were killed on the job due to unsafe working conditions. The sanitation workers, who were predominantly Black, endured low wages, poor working conditions, and discrimination.

Led by the American Federation of State, County, and Municipal Employees (AFSCME) Local 1733 and prominent civil rights leaders such as Dr. Martin Luther King Jr., the striking workers demanded better pay, benefits, and workplace rights. The iconic slogan "I AM A MAN" became their rallying cry, highlighting the dignity and respect they sought as human beings and as workers.

The strike gained national attention and support, drawing thousands of protesters, both Black and white, to march in solidarity. Tragically, Dr. Martin Luther King Jr. was assassinated in the midst of this strike while in Memphis supporting the sanitation workers.

Ultimately, the strike led to the recognition of AFSCME Local 1733 as the official union representing the sanitation workers, securing wage increases, improved working conditions, and labor rights for the workers. The Memphis Sanitation Strike of 1968 highlighted the intersection of racial and economic justice and remains a powerful example of Black-led labor activism in American history.